Similarities and differences in conceptualisation, diagnosis and research Similarities: ASD and Alzheimer’s disease (AD) are neurodevelopmental and neurodegenerative conditions that manifest themselves at different stages of life (two opposite ends of life span, i.e., childhood and old age) (Nadeem et al. 2021; Khan et al. 2016; Rhodus et al. 2020). According to the present trend, they both can be described as neurodivergent conditions. In fact, include both ASD and dementia

Overlaps in biological pathways, clinical features and behavioural expression Although Alzheimer’s disease (AD) and ASD are etiologically distinct conditions , there is growing evidence of significant overlaps in biological and neurological features, and behavioural expression of ASD and AD (and related dementias). Studies also suggest that there are common neurological pathways in both ASD and dementia, particularly involving the immune system and synaptic signaling. A gene

- Hello, where are you? - I am at home. - At home? Where? - I have one home, in England. Why? What’s happened? - Why did you leave without saying ‘goodbye’? It was great when you and your daughter came to see me. We visited friends and had fun. I was preparing your farewell party, but you left. You could have said goodbye… Thus began my conversation with my childhood friend (B.). We have be